Journal: Molecules
Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds
doi: 10.3390/molecules28104220
Figure Lengend Snippet: In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.
Article Snippet: This panel involved human leukemia carcinoma (CCRF-CEM), human ovarian adenocarcinoma (SKOV-3), human breast tumor (MDA-MB-231), human prostate cancer (PC-3), androgen-independent human prostate cancer (DU-145), and human renal carcinoma (iSLK) cell lines.
Techniques: In Vitro, Concentration Assay, Control